Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 34
Filtrar
1.
J Child Adolesc Trauma ; 16(3): 681-697, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37593058

RESUMEN

Negative mental health outcomes have been associated with adverse childhood experiences (ACEs) and intimate partner violence (IPV); however, few studies have identified risk and protective factors across levels of the social ecology that mitigate the onset of psychological distress and suicide risk associated with trauma. This study examines the relationship between ACEs, IPV, and mental health (i.e., psychological distress, suicidal ideation, and suicide attempts) within racial sub-populations of Black American, Latinx, and White adults. An online, cross-section survey was administered to a general population sample of adults in Baltimore and New York City. ACEs, IPV, and mental health outcomes were assessed within racial sub-populations of Black American (N = 390), Latinx (N = 178), and White (N = 339) adults, while accounting for within-group demographic differences. Moderating effects of social support and neighborhood disconnection on the relationship between ACEs, IPV, and mental health outcomes were also assessed. IPV was associated with psychological distress and suicidal ideation for Black and Latinx adults, but not for White adults. ACEs were associated with increased psychological distress for all three groups, and increased odds for suicidal ideation among Black and Latinx adults.. A significant negative interaction effect for neighborhood disconnection was found in the relationship between ACEs and psychological distress for Black adults. Findings highlight the significant mental health burdens of ACEs and IPV within racial and ethnic groups. Neighborhood disconnection may exacerbate psychological distress associated with ACEs among populations most impacted by interpersonal violence and mental health inequalities.

2.
J Interpers Violence ; 38(13-14): 8542-8562, 2023 07.
Artículo en Inglés | MEDLINE | ID: mdl-36866577

RESUMEN

Studies have consistently shown an association between alcohol use in adulthood and intimate partner violence (IPV) perpetration. Yet, no known studies have examined this relationship when considering social support as a potential moderator with a sample of Black men. To address this gap in knowledge, we examined the moderating role of interpersonal social support on alcohol use in adulthood and physical IPV perpetration among Black men. Data for 1,127 Black men were obtained from the National Epidemiologic Survey of Alcohol and Related Condition (NESARC, Wave 2). Descriptive and logistic regression models were run with weighted data using STATA 16.0. Results from logistic regression analyses revealed that alcohol use in adulthood significantly predicted IPV perpetration (odds ratio [OR] = 1.18, p < .001). Interpersonal social support significantly moderated (OR = 1.01, p = .002) the relationship between alcohol use and IPV perpetration among Black men. Additionally, age, income, and perceived stress were significantly associated with IPV perpetration among Black men. Our study findings highlight the role of alcohol use and social support in exacerbating IPV perpetration among Black men, and the need for culturally responsive interventions to address these public health concerns throughout the life course.


Asunto(s)
Violencia de Pareja , Masculino , Humanos , Consumo de Bebidas Alcohólicas/epidemiología , Apoyo Social , Modelos Logísticos , Factores de Riesgo
3.
Violence Against Women ; 28(15-16): 3726-3741, 2022 12.
Artículo en Inglés | MEDLINE | ID: mdl-35763547

RESUMEN

Korean refugee women are at risk of multiple violent victimizations throughout the migration phases. However, migration's association with mental health outcomes has received little scholarly attention. This study examined North Korean refugee women's exposure to polyvictimization-exposure to both gender-based violence (GBV) and intimate partner violence (IPV)-and explored whether polyvictimization is associated with an increased risk of psychological symptoms. Data from a snowball sample of 212 North Korean refugee women were analyzed. Polyvictimization was operationalized as No victimization (0), Only GBV (1), Only IPV (2), and Both GBV and IPV (3). The associations between polyvictimization and depression, suicidal ideation, suicide attempt, and alcohol use disorder were analyzed with multivariate analyses. Results demonstrated that 46.2% experienced GBV in either North Korea or intermediary countries, and 30.9% were victims of IPV from their current intimate partner in South Korea. Approximately 25% were victims of both GBV and IPV. Multivariate analyses revealed that GBV was the most critical factor for mental health outcomes. North Korean refugee women with only GBV or GBV and IPV had significantly higher depressive symptoms and suicidal ideation severity than those without violence victimization. Risk of suicide attempt was also significantly higher among those with only GBV (OR = 16.52, p = .015) or both GBV and IPV (OR = 9.96, p = .048) than those without any violence victimization. Implications for future research and interventions among North Korean refugee women are also discussed.


Asunto(s)
Víctimas de Crimen , Violencia de Pareja , Refugiados , Femenino , Humanos , Refugiados/psicología , República Popular Democrática de Corea , Víctimas de Crimen/psicología , Ideación Suicida
4.
J Interpers Violence ; 37(23-24): NP23202-NP23221, 2022 12.
Artículo en Inglés | MEDLINE | ID: mdl-35404722

RESUMEN

The costs and consequences of intimate partner violence (IPV) and sexual violence (SV) are well-documented; however, little is known about how experiences of violence are connected to specific economic insecurities including food, healthcare, and housing insecurity among both men and women. This study investigates (1) the prevalence of food, healthcare, and housing insecurity across gender and racial groups exposed to IPV and SV and (2) associations between exposure to past-year IPV and SV and past-year food, healthcare, and housing insecurity controlling for confounding factors. A cross-sectional survey design was used in this study. Data from 2010 National Intimate Partner and Sexual Violence Survey (NISVS) were analyzed in a nationally representative sample of men (N = 8079) and women (N = 9970). Logistic regressions were used to model associations between past-year intimate partner and sexual violence and dependent variables of food, healthcare, and housing insecurity. Analyses were stratified by gender and included control variables of age, income, education, and race/ethnicity. Higher rates of food, housing, and healthcare insecurity were found among men and women of color exposed to violence, particularly among respondents who identified as Black/African American, Latinx, American Indian/Alaska Native, and other racial/ethnic minority groups. For men, IPV and SV was associated with higher odds for experiencing food (AOR = 2.40, p <.001), housing (AOR = 2.06, p <.001), and healthcare insecurity (AOR = 2.39, p <.001). For women, IPV and SV was also associated with higher odds for experiencing food (AOR = 2.16, p <.001), housing (AOR = 1.94, p <.001), and healthcare insecurity (AOR = 2.38, p <.001). Findings identify specific economic needs among survivors and suggest that the burdens of IPV and SV are not equitably shared across racial/ethnic populations. Findings can inform policy that aims to reduce inequalities in food, housing, and healthcare associated with IPV and SV.


Asunto(s)
Violencia de Pareja , Delitos Sexuales , Masculino , Femenino , Humanos , Vivienda , Estudios Transversales , Etnicidad , Grupos Minoritarios , Parejas Sexuales , Prevalencia , Atención a la Salud , Factores de Riesgo
5.
Trauma Violence Abuse ; 23(2): 372-389, 2022 04.
Artículo en Inglés | MEDLINE | ID: mdl-32873225

RESUMEN

Intimate partner violence (IPV) is a serious social and public health problem in the United States. Adverse childhood experiences (ACEs) and alcohol use have been found to be associated with IPV perpetration; however, limited studies have examined the interrelationships of these variables among Black men. This is the first known study to systematically review and synthesize studies on the interrelationships of ACEs, alcohol use, and IPV perpetration among Black men. Comprehensive literature searches were conducted in PubMed and six EBSCOhost databases by a research librarian and two researchers. Twenty studies met inclusion criteria: empirical; available in English; included ACEs, alcohol use/substance abuse, and IPV perpetration variables in the analyses; and samples included Black/African American male IPV perpetrators aged ≥ 18 years. ACEs were found to be associated with IPV perpetration among Black men, but findings were mixed regarding the role of alcohol in relation to ACEs and IPV. Numerous ACE factors (1-6) were used across studies. However, findings regarding the co-occurrence of ACE factors are inconclusive because none of the studies examined the cumulative effects of exposure to more than one type of ACE on subsequent IPV perpetration. Implications for policy, practice, and research related to the interrelationships of ACEs, alcohol use, and IPV perpetration are provided. Future work is needed to better explicate the interrelationships among these constructs.


Asunto(s)
Experiencias Adversas de la Infancia , Violencia de Pareja , Adulto , Humanos , Masculino , Estados Unidos/epidemiología
6.
J Interpers Violence ; 37(7-8): NP4718-NP4739, 2022 04.
Artículo en Inglés | MEDLINE | ID: mdl-32960132

RESUMEN

Although parent violence has been extensively investigated in the literature, few studies have examined its link to adult-initiated family violence. This study investigated the relationship between adult-initiated family violence (i.e., child exposure to intimate partner violence [CEIPV] and child abuse) and adolescent-to-parent violence (APV), with a particular focus on the moderating effect of peer attachment on this relationship. A sample of 709 adolescents from the Children and Adolescent Survey (a subset of the 2010 Nationwide Survey of Domestic Violence in South Korea) was used. The survey included measures of child abuse, CEIPV, APV, peer attachment, and demographic characteristics. Multiple regression analysis was conducted to examine the association between two types of adults-initiated family violence and APV. The interaction terms of peer attachment were included in the regression analysis to test its moderating effect. The results indicate that child abuse victimization is significantly associated with APV, but peer attachment significantly buffers the negative effect of child abuse on APV. CEIPV was not significantly associated with APV. The findings of the current study highlight the importance of breaking cycles of violence and improving children's relationships with their peers in preventing parent violence. Counselors and social workers should explore APV perpetrators' child abuse history when conducting interventions. School counseling programs can help reduce adolescents' violent behaviors towards their parents by promoting positive peer relationships and peer bonding.


Asunto(s)
Maltrato a los Niños , Víctimas de Crimen , Violencia Doméstica , Exposición a la Violencia , Violencia de Pareja , Adolescente , Adulto , Niño , Maltrato a los Niños/psicología , Víctimas de Crimen/psicología , Exposición a la Violencia/psicología , Humanos , Violencia de Pareja/psicología , Padres/psicología , Grupo Paritario
7.
J Interpers Violence ; 37(19-20): NP17248-NP17275, 2022 10.
Artículo en Inglés | MEDLINE | ID: mdl-34192964

RESUMEN

This study examined the moderating role of alcohol use on the association between adverse childhood experiences (ACEs) and intimate partner violence (IPV) perpetration among Black men in the United States. We conducted bivariate and logistic regression analyses using data from Wave 2 of the National Epidemiologic Survey of Alcohol and Related Conditions (NESARC). Bivariate results revealed significant relationships between eight of the 10 ACE factors physical neglect; emotional, physical and sexual abuse; witnessing a mother being abused; and having a parent guardian with an alcohol and drug problem and who was incarcerated and IPV perpetration. Similarly, examination of the relationship between ACEs and alcohol use in adulthood also revealed significant associations, with the exception of exposure to emotional neglect, emotional and sexual abuse, and witnessing a mother being abused. Findings from the logistic regression models revealed that alcohol use significantly moderated the relationship between ACEs and IPV perpetration, but only for men exposed to 1, 2, and ≥4 adversities in childhood. However, alcohol use appeared to exacerbate the relationship between ACEs and IPV perpetration for men without childhood adversity. Implications for practice, policy, and areas for further research are discussed.


Asunto(s)
Adultos Sobrevivientes del Maltrato a los Niños , Experiencias Adversas de la Infancia , Maltrato a los Niños , Violencia de Pareja , Trastornos Relacionados con Sustancias , Adulto , Adultos Sobrevivientes del Maltrato a los Niños/psicología , Niño , Maltrato a los Niños/psicología , Humanos , Violencia de Pareja/psicología , Masculino , Estados Unidos/epidemiología
8.
Child Abuse Negl ; 121: 105273, 2021 11.
Artículo en Inglés | MEDLINE | ID: mdl-34419899

RESUMEN

BACKGROUND: Adverse childhood experiences (ACEs) have been linked to subsequent intimate partner violence (IPV) perpetration and alcohol use. Although higher rates of ACEs are found in racial/ethnic minority populations, there is a paucity of research examining ACEs patterns and risk for IPV perpetration and excessive alcohol use among Black men. OBJECTIVE: To identify homogeneous subgroups based on ACEs among Black men using latent class analysis and assessing risk for later IPV perpetration and excessive alcohol consumption in adulthood. METHODS: Using a sample of Black men (n = 2306) from Wave 2 of the National Epidemiologic Survey of Alcohol and Related Conditions (NESARC), we conducted latent class analysis (LCA) to examine their ACEs patterns based on 10 domains. ACE classes were used in logistic regression models to predict IPV perpetration and unhealthy alcohol use. RESULTS: LCA revealed three classes: (1) High Household Dysfunction & Physical Neglect; (2) Physical/Emotional Abuse; and (3) Low ACEs. Men in the High Household Dysfunction & Physical Abuse (OR = 3.95, p < 0.001), and Physical/Emotional Abuse (OR = 2.37, p < 0.001) classes had increased risk for IPV perpetration (ref: Low ACEs class) controlling for sociodemographic factors. No significant association was found between class membership and unhealthy alcohol use. CONCLUSIONS: Our findings highlight the need for interventions aimed at addressing ACEs among Black boys as they increase risk for negative outcomes in adulthood. Future research should explore heterogeneity in ACEs among youth and risk of IPV and explore possible causal mechanisms in the development of IPV among adults who have experienced ACEs.


Asunto(s)
Experiencias Adversas de la Infancia , Violencia de Pareja , Adolescente , Adulto , Etnicidad , Humanos , Violencia de Pareja/psicología , Análisis de Clases Latentes , Masculino , Grupos Minoritarios
9.
Implement Res Pract ; 2: 26334895211050864, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-37089988

RESUMEN

It has been well-documented that the degree to which interventions are implemented with fidelity in typical service settings has varied. Frequently, interventions are developed and tested in highly controlled or early adopter settings. Less attention has been given to what implementation looks like in usual care, and which factors promote practitioners' ability to implement with fidelity. Individuals and organizations implementing interventions in the real world receive varying levels of external supports and may apply a new intervention unaided. The purpose of this mixed-methods study was to explore factors that support implementation as intended in local community agencies. In the quantitative phase of this study, 32 case planners implementing Family Connections (FC), a child maltreatment preventive intervention, completed a survey about their perceptions of practitioner and organizational factors related to fidelity. The survey data were connected to case-level fidelity scores to understand the relationship between perceptions and fidelity. The qualitative phase of this study involved further exploration with nine case planner interviews and two separate focus groups with supervisors and agency leadership. The results of this study suggest that supervision is a key contributor to a practitioner's ability to implement an intervention in usual care. The quantitative and qualitative results suggest supervision, including supervisors' perseverance, proactiveness, knowledge, availability, and skill reinforcement are important components of enhancing a practitioners' ability to learn and use FC. The quantitative results suggest that the level of education was positively associated with fidelity and perceptions of the intervention's limitations may be negatively related to implementation. Additional components that influence implementation for future research emerged from the qualitative phase related to system expectations and policies, individual practitioner attributes, and characteristics of the intervention. Plain Language Abstract: This mixed-methods study sought to understand the impact of practitioner and organizational factors on fidelity of a child maltreatment prevention intervention in community-based settings. The study first asked case planners about their perceptions of practitioner and organizational factors related to fidelity through an online survey. This survey was connected to case-level fidelity scores to understand the relationship between perceptions and fidelity. The qualitative phase of this study involved further exploration with nine case planner interviews and two separate focus groups with supervisors and agency leadership. The results of this study suggest that supervision is a key contributor to a practitioner's ability to implement a maltreatment prevention intervention. Both methods of the study suggest that various aspects of supervision, including supervisors' perseverance, proactiveness, knowledge, availability, and skill reinforcement are important components of enhancing a practitioner's ability to learn and use the intervention. Additional components that influence the implementation for future research emerged from the qualitative phase related to system expectations and policies, individual practitioner attributes, and characteristics of the intervention.

10.
J Interpers Violence ; 36(3-4): NP1335-1358NP, 2021 02.
Artículo en Inglés | MEDLINE | ID: mdl-29295024

RESUMEN

Resilience has been found to attenuate the effects of negative mental health symptomology associated with interpersonal victimization; however, existing research has largely focused on resilience traits, such as individual cognitive and environmental factors that promote resilience. In addition, empirical knowledge on the extent to which resilience mitigates suicidal symptomology associated with interpersonal violence victimization is particularly limited. This study assesses whether the relationship between interpersonal violence (i.e., IPV and nonpartner sexual violence) and mental health symptomology (i.e., depression, psychological distress, and suicidal ideation) is moderated by resilience using a general population sample of women (N = 932). A cross-sectional, observational survey was administered in four U.S. cities (Baltimore, New York City, Philadelphia, and Washington, D.C.). Bivariate results indicated that women exposed to interpersonal violence reported significantly higher rates of suicidal ideation, depression, and psychological distress compared with women without exposure to interpersonal violence. Regression models revealed significant positive associations between interpersonal violence and depression, distress, and suicidal ideation, adjusting for sociodemographics. Resilience did not significantly moderate the relationship between interpersonal violence victimization and any associated mental health outcomes. However, subgroup analyses reveal significant interaction effects between resilience and IPV within specific racial and ethnic minority subgroups, suggesting that attenuating effects of resilience on mental health symptoms (i.e., depression and psychological distress) associated with IPV likely vary across race and ethnicity. Implications for future research and clinical interventions focused on resilience among survivors of interpersonal violence are discussed.


Asunto(s)
Distrés Psicológico , Ideación Suicida , Baltimore , Estudios Transversales , Depresión/epidemiología , Etnicidad , Femenino , Humanos , Grupos Minoritarios , Ciudad de Nueva York , Philadelphia , Violencia
11.
Child Maltreat ; 26(1): 28-39, 2021 02.
Artículo en Inglés | MEDLINE | ID: mdl-32462936

RESUMEN

About half of kinship families live in poverty, and one third of them receive financial assistance such as Temporary Assistance for Needy Families (TANF) and foster care payments. This study selected children who remained in kinship care (N = 267) for three waves from nationally representative data and examined the longitudinal associations among poverty, economic pressure, financial assistance, and children's behavioral health outcomes in kinship care. Results from multilevel mixed-effects generalized linear models indicated that having economic pressure and receiving TANF were associated with increases in kinship children's internalizing and externalizing problems. Receiving TANF exacerbated the effects of poverty on children's externalizing problems, while receiving TANF buffered the negative effects of economic pressure on children's internalizing problems. However, internalizing and externalizing problems were in the normal range, on average. The results imply that child welfare workers should assess kinship families' subjective economic pressure in addition to objective poverty. Furthermore, policy makers should reconsider who receives TANF, how TANF is distributed to kinship families, and whether TANF meets kinship families' needs.


Asunto(s)
Cuidados en el Hogar de Adopción , Pobreza , Niño , Salud Infantil , Protección a la Infancia , Estrés Financiero , Humanos , Asistencia Pública
12.
Child Abuse Negl ; 104: 104483, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-32278928

RESUMEN

BACKGROUND: Children in kinship care may be placed in similar neighborhoods as their birth families, which are predominantly characterized as distressed neighborhoods with high poverty and crime rates, poor-quality housing conditions, and few social resources. Disordered neighborhoods are negatively correlated to social support, but this dynamic may vary by race or ethnicity. However, children's previously established attachment and social bonding may offset the negative effects of distressed neighborhoods on child behavioral health. OBJECTIVES: This study examined the relation between neighborhood disorder and children's internalizing and externalizing problems among children in kinship care and tested caregivers' social support as a potential mediator. Moreover, this study examined if race/ethnicity moderated the pathway from neighborhood disorder to social support, and from social support to children's internalizing and externalizing problems. PARTICIPANTS AND SETTING: This study used NSCAW II wave 3 data for a sample of children in kinship care. METHODS: Univariate, bivariate, and moderated mediation analyses were conducted using STATA 15. RESULTS: Neighborhood disorder was indirectly associated with children's internalizing and externalizing problems through a mediator of social support. No racial/ethnic differences were identified. CONCLUSIONS: Implications for improving social support for kinship caregivers to ameliorate the effects of neighborhood disorder on children's behavioral health are discussed. Implementing effective neighborhood-level interventions could promote positive outcomes for children in kinship care.


Asunto(s)
Conducta Infantil , Etnicidad , Grupos de Población , Problema de Conducta , Características de la Residencia , Apoyo Social , Niño , Preescolar , Crimen , Femenino , Humanos , Masculino , Pobreza
13.
J Child Adolesc Trauma ; 12(2): 221-231, 2019 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-32318194

RESUMEN

Running away from home is a known risk factor for commercial sexual exploitation among youth; however, research has not fully investigated the process by which multiple factors at individual, familial, and extra-familial levels increase youths' risk for runaway behavior. This study applies an ecological risk factor framework to assess risk for runaway behavior among individuals exposed to commercial sexual exploitation and examines mediating relationships between salient risk factors (i.e. substance abuse, insufficient basic needs, having a much older boyfriend/girlfriend) and runaway behavior. A cross-sectional, retrospective survey was administered to individuals involved in the commercial sex industry using Respondent Driven Sampling methods (N = 273). Bivariate results suggested associations between runaway behavior and childhood emotional and physical abuse, having friends who sold sex, having a much older boyfriend/girlfriend, dropping out of school, being worried about where to eat/sleep, homelessness, and frequent alcohol and drug use prior to entering the commercial sex industry. Hierarchical logistic regression revealed that individuals with runaway behavior histories were more likely to have frequently used alcohol and/or drugs and to have insufficient basic needs compared to those did not run away; however, these factors were no longer significant after accounting for having a much older boyfriend/girlfriend. Having an older boyfriend/girlfriend fully mediated the relationship between frequent alcohol and/or drug use and runaway behavior. Findings support the need for community and school-based prevention programs that target these risk factors with a specific focus on healthy dating relationships, which may reduce risk for runaway behavior and subsequent commercial sexual exploitation.

14.
J Trauma Stress ; 31(5): 654-664, 2018 10.
Artículo en Inglés | MEDLINE | ID: mdl-30338572

RESUMEN

Substantial research has linked childhood maltreatment to the development of substance use in adolescence. However, gender differences in the mechanisms that connect child abuse and neglect to substance use remain unclear. In this study, we applied multiple-group structural equation modeling in a sample of 1,161 youths (boys, n = 552; girls, n = 609) from the Longitudinal Studies of Child Abuse and Neglect (LONGSCAN) to examine gender differences in the associations between childhood abuse and neglect exposure from ages 0-12 years and substance use severity at age 18 as mediated by early substance use at age 14 and psychological symptoms (anger, anxiety, and depression) at age 16. In both genders, neglect directly predicted substance use severity, ß = .25, p < .001 for boys and ß = .17, p = .007 for girls; and early substance use, ß = .03, p = .002 for boys and ß = .06, p = .005 for girls; and anger mediated this association, ß = .10, p < .001 for boys and ß = .06, p = .005 for girls. Anger mediated paths from abuse in boys, ß = .06, p = .018. In girls, early substance use mediated the path from abuse to substance use severity, ß = .06, p = .008, with the mediated effect and direct path from abuse to early substance use significantly moderated by gender. For substance use severity, R2 = .26 for girls and R2 = .27 for boys. These findings demonstrate the prominence of neglect in predicting substance use severity and gender differences in paths from abuse.


Asunto(s)
Maltrato a los Niños/psicología , Trastornos Relacionados con Sustancias/etiología , Adolescente , Ira , Ansiedad/epidemiología , Niño , Maltrato a los Niños/estadística & datos numéricos , Preescolar , Depresión/epidemiología , Femenino , Humanos , Lactante , Recién Nacido , Análisis de Clases Latentes , Estudios Longitudinales , Masculino , Autoinforme , Factores Sexuales , Trastornos Relacionados con Sustancias/epidemiología , Trastornos Relacionados con Sustancias/psicología
15.
J Child Adolesc Subst Abuse ; 26(2): 162-173, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28603406

RESUMEN

This study explores gender-specific patterns and transitions of adolescent substance use and delinquency in a sample of youths at ages 12, 15, and 18 (N = 803). Latent transition analysis identified "Primary Delinquent," "Delinquency and Substance Use," and "Low Risk" classes. Females were less likely to be in the "Primary Delinquent" class at age 12 than males. From 15 to 18, females were approximately equally likely to transition from "Primary Delinquent" to both other classes, whereas males were more likely to transition from "Primary Delinquent" to "Delinquency and Substance Use." These gender differences in behavior can inform services.

16.
Hum Mol Genet ; 26(11): 1992-2005, 2017 06 01.
Artículo en Inglés | MEDLINE | ID: mdl-28334933

RESUMEN

Psychiatric disorders arise due to an interplay of genetic and environmental factors, including stress. Studies in rodents have shown that mutants for Disrupted-In-Schizophrenia-1 (DISC1), a well-accepted genetic risk factor for mental illness, display abnormal behaviours in response to stress, but the mechanisms through which DISC1 affects stress responses remain poorly understood. Using two lines of zebrafish homozygous mutant for disc1, we investigated behaviour and functioning of the hypothalamic-pituitary-interrenal (HPI) axis, the fish equivalent of the hypothalamic-pituitary-adrenal (HPA) axis. Here, we show that the role of DISC1 in stress responses is evolutionarily conserved and that DISC1 is essential for normal functioning of the HPI axis. Adult zebrafish homozygous mutant for disc1 show aberrant behavioural responses to stress. Our studies reveal that in the embryo, disc1 is expressed in neural progenitor cells of the hypothalamus, a conserved region of the vertebrate brain that centrally controls responses to environmental stressors. In disc1 mutant embryos, proliferating rx3+ hypothalamic progenitors are not maintained normally and neuronal differentiation is compromised: rx3-derived ff1b+ neurons, implicated in anxiety-related behaviours, and corticotrophin releasing hormone (crh) neurons, key regulators of the stress axis, develop abnormally, and rx3-derived pomc+ neurons are disorganised. Abnormal hypothalamic development is associated with dysfunctional behavioural and neuroendocrine stress responses. In contrast to wild type siblings, disc1 mutant larvae show altered crh levels, fail to upregulate cortisol levels when under stress and do not modulate shoal cohesion, indicative of abnormal social behaviour. These data indicate that disc1 is essential for normal development of the hypothalamus and for the correct functioning of the HPA/HPI axis.


Asunto(s)
Proteínas del Tejido Nervioso/metabolismo , Proteínas del Tejido Nervioso/fisiología , Proteínas de Pez Cebra/metabolismo , Proteínas de Pez Cebra/fisiología , Animales , Codón sin Sentido , Hormona Liberadora de Corticotropina/metabolismo , Hidrocortisona , Sistema Hipotálamo-Hipofisario/metabolismo , Hipotálamo/embriología , Hipotálamo/metabolismo , Larva/metabolismo , Proteínas del Tejido Nervioso/genética , Hipófisis , Sistema Hipófiso-Suprarrenal/metabolismo , Estrés Psicológico , Pez Cebra/metabolismo , Proteínas de Pez Cebra/genética
17.
Psychiatr Serv ; 68(6): 559-565, 2017 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-28142382

RESUMEN

OBJECTIVE: This study examined effects of patient-level and hospital-level characteristics on length and cost of hospital stays among adult patients with psychotic disorders. METHODS: A subsample of 677,684 adult patients with a primary diagnosis of a psychotic disorder was drawn from the 2003-2011 Healthcare Cost and Utilization Project Nationwide Inpatient Sample. A nationally representative survey design and census data were used to calculate hospitalization rates. Multilevel models examined variation in length and cost of stay in relation to individual (age, sex, race-ethnicity, household income, payer source, and illness severity) and hospital (region, urban or rural location, ownership, teaching status, and size) characteristics. RESULTS: Admission rates differed dramatically by region, with higher rates in the Northeast. Compared with white patients, African Americans had higher admission rates but shorter stays and lower costs, and Asians/Pacific Islanders and Native Americans had longer stays. Longer stays were also associated with higher versus lower illness severity and use of Medicaid and Medicare versus private insurance. Length and cost of stays were greater in Northeast hospitals and in public hospitals. CONCLUSIONS: Strong differences were noted in use of hospitalization to treat psychotic disorders. Higher admission rates and longer stays in the Northeast were striking, as were differences in admission rates and length of stay for African-American patients compared with white patients. Future research should investigate the appropriateness of acute care use from an overuse (Northeast) and underuse (West) perspective. Findings raise questions about the effects of health reform on adult acute care use and have implications for mental health and hospital policy.


Asunto(s)
Costos de la Atención en Salud/estadística & datos numéricos , Hospitales/estadística & datos numéricos , Tiempo de Internación/estadística & datos numéricos , Admisión del Paciente/estadística & datos numéricos , Trastornos Psicóticos/economía , Adolescente , Adulto , Distribución por Edad , Etnicidad/estadística & datos numéricos , Femenino , Reforma de la Atención de Salud , Humanos , Seguro de Salud , Masculino , Medicaid/economía , Medicare/economía , Persona de Mediana Edad , Análisis Multinivel , Admisión del Paciente/tendencias , Trastornos Psicóticos/epidemiología , Distribución por Sexo , Estados Unidos/epidemiología , Adulto Joven
18.
Child Youth Serv Rev ; 67: 57-66, 2016 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-27840465

RESUMEN

While marriage and childbirth are generally considered positive adult outcomes, it is not clear that this holds true among low income young women. Beyond adolescent parenting, little empirical data exists on various types of family formation in this population. The aims of this study were twofold: (1) to understand predictors of type of family formation (e.g., none, childrearing, marriage, or both) among 4,385 young women with childhood histories of poverty and/or maltreatment; and (2) to explore whether family formation patterns were associated with negative adult behavioral and health outcomes. Results of the AIM 1 multinomial regression analysis of family formation indicated that the likelihood of childrearing with or without marriage increased with an increase in the number of adolescent risk behaviors after controlling for the maltreatment and/or poverty histories. Among women with maltreatment histories, early onset maltreatment was associated with childrearing or marriage compared to no family. Among previously maltreated women, predictors of family formation varied according to prior poverty history. AIM 2 Cox regression results indicated that having children with or without marriage was associated with a higher risk of negative outcomes after controlling for maltreatment and adolescent risk factors. Bivariate analyses suggested that most of the increased risk was associated with having at least two children. Findings underscore the importance of preventing adolescent risk behaviors among low income and maltreated girls as well as early and unplanned births among vulnerable young adult women.

19.
Health Care Manag (Frederick) ; 35(3): 266-79, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27455369

RESUMEN

Turnover among frontline hospital service workers can disrupt organizational effectiveness, reduce profitability, and limit the ability to provide high-quality, patient-centered care. This concern is compounded by the increasing reliance on frontline supervisors to manage this workforce, often without necessary training and support. However, research addressing the relationship between frontline supervisor support and intent to turnover among service workers and the process by which these variables are related is limited. By surveying 270 housekeeping and dietary service workers employed at 2 US hospitals, this study examined the relationship between supervisor support and turnover intent and assessed the mediating role of affective commitment between supervisor support and intent to turnover. Turnover intentions were lower for workers who reported greater levels of supervisor support and affective commitment; both supervisor support and affective commitment were significant predictors of turnover intent when tested individually. However, when controlling for affective commitment, supervisor support no longer predicted turnover intent, indicating that affective commitment fully mediated the relationship between supervisor support and intent to turnover. Implications for further research and organizational practice are discussed.


Asunto(s)
Organización y Administración/normas , Administración de Personal , Reorganización del Personal/estadística & datos numéricos , Personal de Hospital/psicología , Apoyo Social , Humanos , Atención Dirigida al Paciente , Encuestas y Cuestionarios
20.
Subst Use Misuse ; 50(14): 1814-25, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26646723

RESUMEN

BACKGROUND: In adolescence, internalizing (e.g., anxious, depressive, and withdrawn) and externalizing (e.g., aggressive, oppositional, delinquent, and hyperactive) symptoms are related with alcohol use. However, the directionality among internalizing symptoms, externalizing symptoms, and alcohol use during adolescence is equivocal. Moreover, gender differences and similarities among these behaviors are not definitive in existing literature. OBJECTIVES: This study examined longitudinal relationships between internalizing and externalizing symptoms and past-month alcohol use among adolescent boys and girls. METHODS: Using longitudinal survey data from a study of community-dwelling adolescents (n = 724), we estimated cross-lagged structural equation models to test relations between internalizing and externalizing symptoms (as measured by the Youth Self Report, YSR [Achenbach, 1991]) and self-report alcohol use in the past month among adolescents. Gender differences were tested in a multiple group structural equation model. RESULTS: Alcohol use at age 12 was a predictor of internalizing and externalizing symptoms at age 15 for both boys and girls. With regard to gender differences, girls demonstrated an association between internalizing symptoms and drinking at age 12, whereas boys showed a stronger association between externalizing symptoms and drinking at age 18. CONCLUSIONS/IMPORTANCE: Early alcohol use is problematic for youth, and results of this study lend support to prevention programs for youth. Preventing or curbing early drinking may offset later externalizing and internalizing symptoms, as well as ongoing alcohol use, regardless of gender.


Asunto(s)
Emociones , Consumo de Alcohol en Menores/psicología , Consumo de Alcohol en Menores/estadística & datos numéricos , Adolescente , Distribución por Edad , Agresión , Consumo de Bebidas Alcohólicas/epidemiología , Consumo de Bebidas Alcohólicas/psicología , Ansiedad/psicología , Chicago/epidemiología , Niño , Depresión , Femenino , Humanos , Delincuencia Juvenil , Estudios Longitudinales , Masculino , Pruebas Psicológicas , Análisis de Regresión , Distribución por Sexo
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA
...